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Albert Hofmann

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Albert Hofmann was born on January 19, 1906 in Baden, Switzerland. He was a chemist who discovered the drug Lysergic Acid Diethylamide (LSD) and its properties, as well as its psychedelic effects. This article explores the life and career of Albert Hofmann, his famous discovery of LSD, and his later interests in meditation and nature.


Early life

Hofmann was born in Baden, Switzerland in 1906. His father, Gustav, was a pharmaceutical manufacturer who established his own company in 1928. Due to his father’s work with chemicals, Hofmann was exposed to many psychedelic substances from a young age. He also became interested in plants and their effects on people as well. He graduated from school in 1925 with a degree in chemistry, then went on to attend the University of Zurich where he received his doctorate in 1929. That same year, he started working for the Sandoz Pharmaceutical Company.


Discovery of LSD

Hofmann’s first assignment at Sandoz was to develop synthetic potential hormones and adrenal cortical steroids. In 1935, he attempted to synthesize the active principles of the Ephedra and Rauwolfia plants, but instead synthesized Lysergic Acid Diethylamide (LSD). It remained just an experimental compound and a laboratory curiosity until five years later, when Hofmann accidentally ingested the chemical on a lab bench and experienced what would become a lifetime of self-discovery and research. Afterward, Hofmann devoted himself to the study and investigation of LSD, describing the experience of its discovery as “the most significant experience of my research career.” Although he believed in its potential use as a psychotherapeutic tool, the idea was not popular among scientists at the time. In the following years, Hofmann continued to explore the effects of LSD, including its connection to the ergot fungus. It was during these experiments that he discovered that not only did the chemical induce hallucinations, but also that there was a chemical connection between LSD and ergot.


Later Life

Hofmann was a researcher and scientist for most of his life. He retired from his position at Sandoz in 1971, but still maintained a lab space there. In the decade that followed, he traveled and lectured around the world. During this time, he also developed an interest in Eastern religions and meditation, which became central to his later life. Toward the end of his life, Hofmann also became interested in natural history and botany. In the late 1980s, he suffered a fall and broke several bones, which led him to focus his attention on his recovery. He died on April 29, 2008 after a short illness at the age of 101.


Legacy

Hofmann’s discovery of LSD and his research on its effects were a revolutionary and controversial break from prior research on hallucinogens. Prior work focused on identifying and understanding the effects of different substances in the hope of finding medical or therapeutic use for them. Hofmann’s work, on the other hand, focused on the psychedelic experience, including the hallucinations and other altered mental states that occur during the experience. Hofmann’s work also introduced the concept of the “trip,” referring to the subjective experience of the psychedelic journey. Through his research, Hofmann also introduced the idea that psychedelic substances allow people to discover new things about themselves, including repressed memories and feelings.


Bottom line

Albert Hofmann is remembered for his discovery of LSD and its psychedelic effects, as well as his later interests in meditation and botany. Through his work, Hofmann contributed to the popularization of psychedelic substances in Western culture and psychology, as well as the idea that these substances allow people to discover new things about themselves. Although LSD was first synthesized in the 1930s, Hofmann’s research and published findings on the chemical helped to popularize its use as a psychedelic drug in the 1950s and 1960s. His work with psychedelics and their effects has also been used to inform modern therapeutic practices and psychotherapies, as well as psychology and mental health more broadly.

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